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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Accepted calculation method in the absence of experimental study.
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
not specified
Test organisms (species):
activated sludge of a predominantly domestic sewage
Water media type:
freshwater
Total exposure duration:
3 h
Key result
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
> 1 000 mg/L
Conc. based on:
act. ingr.
Basis for effect:
growth inhibition

The prediction was based on dataset comprised from the following descriptors: EC10
Estimation method: Takes average value from the 5 nearest neighbours
Domain  logical expression:Result: In Domain

((("a" and ( not "b") )  and ( not "c") )  and ("d" and "e" )  )

Domain logical expression index: "a"

Similarity boundary:Target: C=Cc1ccc(S(=O)(=O)O{-}.[Na]{+})cc1
Threshold=50%,
Dice(Atom pairs)
Atom type; Count H attached; Hybridization

Domain logical expression index: "b"

Referential boundary: The target chemical should be classified as Group 12 - Trans.Metals Zn,Cd,Hg OR Group 15 - Metalloids As,Sb OR Group 15 - Nitrogen N OR Group 17 - Halogens Br OR Group 17 - Halogens Cl OR Group 17 - Halogens F OR Group 17 - Halogens F,Cl,Br,I,At OR Group 17 - Halogens I by Chemical elements

Domain logical expression index: "c"

Referential boundary: The target chemical should be classified as Aldehydes (Acute toxicity) OR Esters (Acute toxicity) OR Phenols (Acute toxicity) by US-EPA New Chemical Categories

Domain logical expression index: "d"

Parametric boundary:The target chemical should have a value of log Kow which is >= -2.4

Domain logical expression index: "e"

Parametric boundary:The target chemical should have a value of log Kow which is <= -1.5

Validity criteria fulfilled:
yes
Conclusions:
Growth inhibition Effect Concentration (EC10) for activated sludge for sodium p-styrenesulfonate is estimated to be more than 1000 mg/L.
Based on this result it can be concluded that sodium p-styrenesulfonate is not toxic to microorganism in sludge based on creteria given by CLP regulation.
Executive summary:

Growth inhibition Effect Concentration (EC10) for activated sludge for sodium p-styrenesulfonate is estimated to be more than 1000 mg/L.

Based on this result it can be concluded that sodium p-styrenesulfonate is not toxic to microorganism in sludge based on creteria given by CLP regulation.

Description of key information

Growth inhibition Effect Concentration (EC10) for activated sludge for sodium p-styrenesulfonate has been estimated by QSAR to be more than 1000 mg/L.

Based on this result it can be concluded that sodium p-styrenesulfonate is not toxic to microorganism in sludge based on creteria given by CLP regulation.

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information