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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Description of key information

The dissociation constant has been measured on two similar products.
The pKa of the first substance (Tetrakis(hydroxymethyl) phosphonium chloride, oligomeric reaction products with urea) was determined to 4,93 at 22°C (Kühne, 2010).
The pKa of the second substance (Tetrakis (hydroxymethyl) Phosphonium Chloride (THPC)) was estimated to 5,48 at 20°C (Younis, 2010).

Key value for chemical safety assessment

Additional information

Based on dissociation constant measured on two similar products, the registered reaction product has to be considered in its dissociated form at environmental pH.