Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
EC number: 943-503-9 | CAS number: -
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: According to ECHA Practical Guide 6 the maximum score for read across is rel. 2
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Gene expression changes in the immature rat uterus: Effects of uterotrophic and sub-uterotrophic doses of bisphenol A
- Author:
- Ashby J, Odum J
- Year:
- 2 004
- Bibliographic source:
- Toxicological Sciences. 82(2): 458-467
- Reference Type:
- publication
- Title:
- The OECD program to validate the rat uterotrophic bioassay. phase 2: coded single-dose studies
- Author:
- Kanno J, Onyon L, Peddada S, Ashby J, Jacob E, Owens W
- Year:
- 2 003
- Bibliographic source:
- Environmental Health Perspectives. 111: 1550-1558
- Reference Type:
- publication
- Title:
- The OECD program to validate the rat uterotrophic bioassay. phase 2: dose-response studies
- Author:
- Kanno J, Onyon L, Peddada S, Ashby J, Jacob E, Owens W
- Year:
- 2 003
- Bibliographic source:
- Environmental Health Perspectives. 111: 1530-1549
Materials and methods
Test material
- Reference substance name:
- 4,4'-isopropylidenediphenol
- EC Number:
- 201-245-8
- EC Name:
- 4,4'-isopropylidenediphenol
- Cas Number:
- 80-05-7
- Molecular formula:
- C15H16O2
- IUPAC Name:
- 2,2-bis(4-hydroxyphenyl)propane
Constituent 1
Results and discussion
Any other information on results incl. tables
The substance contains approx. 15 % 2,2-bis(4-hydroxyphenyl)propane (CAS No 80-05-7), therefore data of 2,2-bis(4-hydroxyphenyl)propane are relevant for toxicological assessment and were thus included in the IUCLID.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
