Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
neurotoxicity
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: According to ECHA Practical Guide 6 the maximum score for read across is rel. 2

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
4,4'-isopropylidenediphenol
EC Number:
201-245-8
EC Name:
4,4'-isopropylidenediphenol
Cas Number:
80-05-7
Molecular formula:
C15H16O2
IUPAC Name:
2,2-bis(4-hydroxyphenyl)propane

Results and discussion

Any other information on results incl. tables

The substance contains approx. 15 % 2,2-bis(4-hydroxyphenyl)propane (CAS No 80-05-7), therefore data of 2,2-bis(4-hydroxyphenyl)propane are relevant for toxicological assessment and were thus included in the IUCLID.

Applicant's summary and conclusion