Registration Dossier
Registration Dossier
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EC number: 203-643-7 | CAS number: 109-06-8
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is readily biodegradable in the environment, does not have a propensity to adhere to soils or sediments, and has a low potential for bioaccumulation.
2-Methylpyridine (alpha-picoline, CAS 109 -06 -8) is a member of a category with is utilized for “read-across” to fill data gaps and for risk assessment for hazard identification. The category of pyridine and alkyl pyridine derivatives is comprised of pyridine (CAS 110 -86 -1), 2-methylpyridine (CAS 109 -06 -8), 3-methylpyridine (CAS 108 -99 -6) and 4-methylpyridine (CAS 108 -89 -4). The foundation of the category is a common functional group (the pyridine unsaturated ring structure) and similar physico-chemical properties, environmental fate and toxicity, and mammalian toxicity. Similar toxicological properties derive from physico-chemical parameters and common pathways of metabolism and elimination among all members of the category. Three of four members of this category have harmonized classification and labelling. Read-across for non-harmonized endpoints is adequate for risk assessment purposes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
