Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Moiseenok AG et al.
Year:
1979
Bibliographic source:
Khim Farm Zh 13: 22; cited in: BIBRA Toxicity Profile Pantolactone, 1995

Materials and methods

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data given
No. of animals per sex per dose:
no data given
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
600 mg/kg bw
Mortality:
no data given
Clinical signs:
no data given
Body weight:
no data given
Gross pathology:
no data given

Applicant's summary and conclusion