Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP compliant study conducted according to OECD Guidelines, with no or minor deviations.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Qualifier:
according to
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
Name: Linalool Oxide
Batch No.: PE00097239
Purity: 98.5 % (Sum of cis- and trans- isomers)
Expiry date: 2016-08-27

Please note that although the substance is described in the report with the IUPAC name: 2-(5-methyl-5-vinyltetrahydrofuran-2-yl)propan-2-ol related to the CAS number 1365-19-1, recent analytical data had been determined the substance to be a multi-constituent 2-(tetrahydro-5-methyl-5-vinyl-2-furyl)propan-2-ol related to the CAS number 60047-17-8.

As the chemical manufacturing process has not changed since the report was written, the recent analytical information is relevant to the batch which was tested.

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
The concentrations of the test item Linalool Oxide were determined at the start of the exposure intervals (0 h and 72 h) and at the end of the exposure intervals (24 h and 96 h) of the tested limit concentration of the test item Linalool Oxide and the control via GC-MS.

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Cyprinus carpio

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96
Remarks on exposure duration:
hours

Test conditions

Nominal and measured concentrations:
The concentrations of the test item Linalool Oxide were determined at the start of the exposure intervals (0 h and 72 h) and at the end of the exposure intervals (24 h and 96 h) of the tested limit concentration of the test item Linalool Oxide and the control via GC-MS.

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
All validity criteria of the test guideline were met.
Conclusions:
Based on nominal test item concentration , LC50 > 100 [mg/L]