Registration Dossier
Registration Dossier
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EC number: 408-200-3 | CAS number: 63187-91-7 FRESCOLAT MGA
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
No experimental determination of the Log Koc has been performed, as, based on the substance's experimentally determined log Kow value of 3, it can be expected that the substance will have a low potential for adsorption. This is further confirmed by the results of the EpiSuite KOCWIN QSAR:
The log Koc value as estimated by EpiSuite's KOCWIN is:
1.48 (MCI method)
2.01 (Log Kow method)
For the purpose of the risk assessment the value calculated via the MCI method is retained, as the model's accuray and domain description states that the MCI method is somewhat more accurate.
Key value for chemical safety assessment
- Koc at 20 °C:
- 30.2
Additional information
No experimental determination of the Log Koc has been performed, as, in accordance with Column 2 of REACH Annex VIII, the study does not need to be conducted if, based on the physicochemical properties, the substance can be expected to have a low potential for adsorption. As the experimentally determined log Kow of the substance is 3, the adsorption potential of the substance is low.
This is confirmed by the results of the EpiSuite KOCWIN QSAR.
EpiSuite KOCWIN is a widely used and accepted model, and menthon 1,2 -glycerin ketal was found to be within the applicability domain of the QSAR.
The calculated log Koc values are 1.48 (MCI method), and 2.01 (log Kow method).
For the purpose of the risk assessment the value calculated via the MCI method is retained, as the model's accuray and domain description states that the MCI method is somewhat more accurate.
Based on this log Koc value, it can be concluded that the substance has a low tendency for adsorption to soil and is very highly mobile in soil according to the classification scheme of Mc Call et al. (1981).
[LogKoc: 1.48]
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