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Diss Factsheets
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EC number: 204-496-1 | CAS number: 121-73-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer reviewed journal
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- 14 day Long term toxicity tests were carried out to test the toxic effects of 1Chloro-3-nitrobenzene on fresh water crustacean daphnia magna.
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data available - Analytical monitoring:
- not specified
- Details on sampling:
- - Concentrations:
26 mg/l and 4.5mg/l - Vehicle:
- not specified
- Details on test solutions:
- No data available
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea - Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 14 d
- Post exposure observation period:
- - Renewal rate of test solution (frequency/flow rate): Daily
- Hardness:
- No data available
- Test temperature:
- No data available
- pH:
- No data available
- Dissolved oxygen:
- No data available
- Salinity:
- No data available
- Nominal and measured concentrations:
- No data available
- Details on test conditions:
- No data available
- Reference substance (positive control):
- not specified
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- 22.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Immobilization
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- 3.82 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Immobilization
- Details on results:
- No data available
- Results with reference substance (positive control):
- No data available
- Reported statistics and error estimates:
- No data available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Based on the immobilization the LC50 and EC50 was determined to be 22.1mg/l and 3.82mg/l respectively. As it is a chronic study substance may not be classified.
- Executive summary:
Long term toxicity study was conducted to test the effects of 1 chloro 3 nirobenzene on daphnia magna for 14 days .based on the immobilization the LC50 and EC50 was determined to be 22.1mg/l and 3.82mg/l respectively.
Reference
Description of key information
Based on the immobilization the LC50 and EC50 was determined to be 22.1 mg/l and 3.82 mg/l respectively. As it is a chronic study substance may not be classified.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 22.1 mg/L
Additional information
Based on the value aquired from peer reviewed journal,long term toxicity of aquatic invertebrates was discribed as below:
Long term toxicity study was conducted to test the effects of 1-chloro-3-nitrobenzene on daphnia magna for 14 days .Based on the immobilization the LC50 and EC50 was determined to be 22.1mg/l and 3.82mg/l respectively.
Long term toxicity study was conducted to test the effects of 1-chloro-3-nitrobenzene on fresh water invertebrates daphnia magna for 21 days. Feeding was provided to the daphnids 3x108C.pyrenoidosa cells/l/day.Based on the mortality the LC50 was determined to be 2.0mg/l for 21days chronic exposure. The substance may not be classified as it is chronic study.
Based on the effect concentrations we can consider that the test substance 1-chloro-3-nitrobenzene has no chronic effect on aquatic invertebrates and can be considered as not classified as per CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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