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EC number: 201-642-6 | CAS number: 85-91-6
MNMA was hydrolyzed byguinea pigs liver microsomes to produceN-Methyl Anthranilic acid.MNMA was also N-Demthylated byGuinea pigs liver microsomes & cytosol to form anthranilic acid (AA).
In vitro study of hepatic metabolism of Methyl N Methylanthranilate in guinea pigs liver microsomes was conducted wherein the kinetic analysis indicated that Vmax/Km values were 7.4 fold higher in microsomes than in cytosol. Vmax/Km values reflect the intrinsic clearance potential after hydrolysis and thus the bio-accumulation potential ofMethyl N Methylanthranilate (MNMA)is expected to be low.
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