Registration Dossier
Registration Dossier
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EC number: 246-014-2 | CAS number: 24085-08-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Test performed according to OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test) and GLP
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
The applied concentrations of test substance were plotted against the resulting percentage inhibition observed. An EC50 value for Glycyl (GR34000A could not be estimated, but must be greater than the highest tested concentration (1000 mg/L).
Samples of activated sludge were exposed to Glycyl (GR34000A) at nominal concentrations ranging from 1.0 to 1000mg/L, and their respiration rates measured after 3 hours contact time. No significant inhibition was observed in the preliminary rangefinder test, some respiration rates were slightly elevated in the presence of test substance. Further experimentation was not considered necessary.
The EC50of the reference inhibitor, 3,5 -dichlorophenol, lay between 5and 30mg/L, indicating that the sludge used in this study was neither unusually sensitive nor abnormally robust.
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