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EC number: 251-974-0 | CAS number: 34375-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- data is from safety assessment reports
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Principles of method if other than guideline:
- The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs.
- GLP compliance:
- not specified
- Type of method:
- static method
- Specific details on test material used for the study:
- Name of test material (as cited in study report): 2-[(Hydroxymethyl)amino] ethanol
Molecular formula: C3H9NO2
Molecular weight: 91.1091 g/mol
Smiles notation: CN(CCO)O
InChI: 1S/C3H9NO2/c14(6)235/h56H,23H2,1H3
Substance Type: Organic
Physical State: Liquid - Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 2 116 Pa
- Remarks on result:
- other: no other details mentioned
- Test no.:
- #2
- Temp.:
- 20 °C
- Vapour pressure:
- 1 585 Pa
- Remarks on result:
- other: no other details mentioned
- Conclusions:
- The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs
The vapor pressure of 2-[hydroxy(methyl)amino]ethanol at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively. - Executive summary:
The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs
The vapor pressure of the test chemical was determined using the static method presented in the guideline. An instrument constructed by Case Consulting Laboratories, Inc. was used. The zero-indicator and nitrogen pressures were measured using pressure transducers.
The test substance was places in a glass, round-bottomed flask and attached to the instrument. The test substance was degassed by immersing the flask in a dry ice/ethanol bath and applying a high vacuum. The test substance was warmed to room temperature under vacuum, cooled again in dry ice/ethanol and the limited head space was evacuated.
The pressure produced by the test substance at a particular temperature was recorded. The temperature was raised by an arbitrary amount (~9°C), the system brought to thermodynamic equilibrium and the new pressure recorded. This cycle was repeated for a total of four data points. The log of the pressure was plotted against the reciprocal of the absolute temperature. Vapor pressures at 20 and 25°C were calculated from this curve.
No statistics methods were applied.
The vapor pressure of 2-[hydroxy(methyl)amino]ethanol at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.
Reference
Description of key information
The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLP.
The vapor pressure of 2-[hydroxy(methyl)amino]ethanol at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.
Key value for chemical safety assessment
- Vapour pressure:
- 1 585 Pa
- at the temperature of:
- 20 °C
Additional information
The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs.
The vapor pressure of 2-[hydroxy(methyl)amino]ethanol at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.
MPBPVP v1.43 was used to estimate the vapor pressure of 2-[hydroxy(methyl)amino]ethanol. The estimated vapour pressure of 2-[hydroxy(methyl)amino]ethanol at 25 deg C was 3.07 Pa.
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