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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from ECOSAR model
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
Long term toxicity of test chemical were determine on the basis of immobilisation of daphnia magna.
GLP compliance:
no
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Details on test organisms:
- Common name: Water flea
Test type:
not specified
Water media type:
freshwater
Total exposure duration:
21 d
Reference substance (positive control):
not specified
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
28.833 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
immobilisation
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of no effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 28.833 mg/l for aquatic invertebrate for 21 days of exposure duration.
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 28.833 mg/l for aquatic invertebrate for 21 days of exposure, it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Description of key information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 28.833 mg/l for aquatic invertebrate for 21 days of exposure, it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
28.83 mg/L

Additional information

Long term toxicity to aquatic invertebrate:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be28.833mg/l for aquatic invertebrate for 21 days of exposure, it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.