Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-03-06 – 2017-03-06
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Justification for type of information:
Data from experimental study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD 122
Principles of method if other than guideline:
A pH meter is essentially a voltmeter with high input impedance which measures the voltage of an electrode sensitive to the hydrogen ion concentration, relative to another electrode which exhibits a constant voltage
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Details on test material:
- Name of test material (as cited in study report): Ethyl butyrate
- Molecular formula : C6H12O2
- Molecular weight :116.16 g/mol
- Smiles notation : C(=O)(CCC)OCC
- InChl : 1S/C6H12O2/c1356(7)842/h35H2,12H3
- Substance Type: Organic
- Physical State: Liquid

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 0001
- Expiration date of the lot/batch:July; 2021
- Manufacturing Date: July; 2016

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Test Item and prepared formulation(s) were stored at ambient temperature.

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: The test item was used undiluted and as supplied by the Sponsor.

OTHER - Safety Precautions: Safety precautions included use of protective clothing, gloves, masks and eye protection (glasses).
Specific details on test material used for the study:
- Name of test material: Ethyl Butyrate
- Molecular formula: C6H12O2
- Molecular weight: 116.158 g/mol
- Smiles notation: CCC(=O)OCC
- InChl: 1S/C6H12O2/c1-3-5-6(7)8-4-2/h3-5H2,1-2H3
- Substance type: organic
- Physical state: Liquid

Results and discussion

pH value
Key result
pH value:
4.18
Temp.:
29 °C
Concentration:
1 other: %w/v
Acidity or alkalinity
Key result
Acidity or alkalinity:
acidity
Value:
4.18
Remarks on result:
other: No other detail available

Applicant's summary and conclusion

Conclusions:
The pH of 1% w/v emulsion of the test item was 4.18 at 29 °C.
Executive summary:

The pH determination of test item was done following OECD guideline 122. pH of 1% w/v emulsion was measured with the help of pH meter and it was observed to be 4.18 at 29 °C.