Registration Dossier
Registration Dossier
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EC number: 276-763-0 | CAS number: 72676-55-2
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation in water: Screening
Key Study:
In an OECD Guideline 301B study, conducted according to GLP, 5,5'-Dithiodi-1,3,4-thiadiazole-2(3H)-thione achieved 0% biodegradation after 28 days and is considered not readily biodegradable (Envigo Research Limited, 2016).
Biodegradation in water and sediment: simulation tests
Data waiving:
According to column 2 of annexes IX and X of REACH regulation EC 1907/2006, further biotic degradation testing shall be proposed by the registrant if the chemical safety assessment according to annex I indicates the need to investigate further the degradation of the substance and its degradation products. According to the risk assessment, the risks for all the compartments are considered all acceptable (all RCR are below 1 in all exposure scenarii). Since the CSR does not indicate the need to investigate further hazard and risks for all the compartments studies are therefore waived in compliance with column 2 of annexes IX and X of REACh regulation EC 1907/2006.
Furthermore, according to ECHA’s guidance on information requirements and chemical safety assessment, chapter R11 (v3.0 ; June 2017) no further investigations on the degradation of the substance and its degradation products are required for the PBT/vPvB assessment. Indeed, according to the Figure R.11—4: Integrated assessment and testing strategy for B-assessment the substance is not B nor vB (log Kow < 2) therefore the substance is not PBT/vPvB.
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