Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 96-91-3
Author:
Danish (Q)SAR Database
Year:
2016
Bibliographic source:
Database developed by National Food Institute, Technical University of Denmark, with support from the Danish Environmental Protection Agency, the Nordic Council of Ministers and the European Chemicals Agency.

Materials and methods

Principles of method if other than guideline:
The prediction is done using Danish (Q)SAR Database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-amino-4,6-dinitrophenol
EC Number:
202-544-6
EC Name:
2-amino-4,6-dinitrophenol
Cas Number:
96-91-3
Molecular formula:
C6H5N3O5
IUPAC Name:
2-amino-4,6-dinitrophenol
Details on test material:
SMILES: c1(N)c(O)c(N(=O)=O)cc(N(=O)=O)c1

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
7.371 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion

Conclusions:
Based on the QSAR prediction done using the Danish (Q)SAR Database, the 48 hours EC50 was estimated to be 7.370772 mg/L on Daphnia Magna for substance 2-amino-4,6-dinitrophenol with immobilization effects.
Executive summary:

Based on the QSAR prediction done using the Danish (Q)SAR Database, the 48 hours EC50 was estimated to be 7.370772 mg/L on Daphnia Magna for substance 2-amino-4,6-dinitrophenol with immobilization effects.