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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from authoritative database
Justification for type of information:
Data is from authoritative database
Qualifier:
according to
Guideline:
other: As mention below
Principles of method if other than guideline:
Study was assess to evaluate the nature and effect of test chemical on the growth of algae for the exposure period of 72 hrs.
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material: Tridecyl alcohol
- IUPAC name: 1-Tridecanol
- Molecular formula: C13H28O
- Molecular weight: 200.37 g/mole
- Smiles notation: C(CCCCCCO)CCCCCC
- InChl: 1S/C13H28O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14/h14H,2-13H2,1H3
- Substance type: Organic
- Physical state: Solid
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
other: Green algae
Test type:
static
Water media type:
freshwater
Total exposure duration:
72 h
Reference substance (positive control):
not specified
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.012 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: No data available
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.003 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: Other details not known
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.09 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Biomass and area under the growth curve
Remarks on result:
other: Other details not known
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.017 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: Biomass and area under the growth curve
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
Based on the growth rate inhibition of green algae due to the exposure of tes chemical and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l.
Executive summary:

Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.

Description of key information

Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.

Key value for chemical safety assessment

EC50 for freshwater algae:
0.012 mg/L

Additional information

Based on the various experimental data for the target chemical study have been reviewed to determine the toxic nature on the growth of aquatic algae and cyanobacteria. The studies are as mentioned below:

 

In the first key study for the target chemical was described in authorative database,

Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.012 mg/l and 0.0029 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.09 mg/l and 0.017 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 as per the CLP classification criteria.

 

Similarly in the second supporting study for the target chemical from secondry source says that the chemical was toxic. Study was assess to evaluate the nature and effect of test chemical on the growth of algae for the exposure period of 72 hrs. After the exposure of chemical for 72 hrs, the EC50 was determine to be 0.1-1 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 and chronic 1 as per the CLP classification criteria.

 

The fourth study consider for the test chemical from authorative database. Study was assess to evaluate the nature and effect of test chemical on the growth of green algae for the exposure period of 72 hrs. Study was conducted under the static system. After the exposure effect was determine. Based on the growth rate inhibition of green algae due to the exposure of test chemical , the EC50 and NOEC was 0.56 mg/l and 0.028 mg/l. But on the basis of Biomass and area under the growth curve, the EC50 and NOEC was determine to be 0.72 mg/l and 0.09 mg/l. Based on the EC50, test chemical was concluded as toxic and can be consider to be classified as aquatic acute 1 and chronic 1 as per the CLP classification criteria.

 

Based on the experimental data for the test chemical it can be concluded that the substance is considered to be toxic to aquatic algae and cyanobacteria and classified as aquatic acute 1 and chronic 1 category as per the CLP classification criteria.