Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: Literature based toxicokinetic assessment
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short abstract available

Data source

Materials and methods

Objective of study:
other: Assessment of toxicokinetic behaviour
Test guideline
Qualifier:
no guideline available
GLP compliance:
no

Test material

Radiolabelling:
no

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: unlikely to be available for metabolism or excretion
The substance is unlikely to be absorbed orally or dermally, and is unlikely to be inhaled and retained.
Executive summary:

Given the solubility profile and particle size, the substance is unlikely to be absorbed orally or dermally, and is unlikely to be inhaled and retained. Given the solubility of the material, it is also unlikely to become available for metabolism or excretion. If particles lodge in the alveolus following inhalation, they will be dealt with largely as insoluble particulates, and if the substance is administered orally it is likely to appear in faeces unabsorbed.