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Toxicity to microorganisms

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Description of key information

3 h EC50 in actiavted sludge > 1000 mg ai/L with the NOEC at 1000 mg ai/L.

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L
EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

The acute toxicity of the test material to microorganisms was investigated in accordance with the standardised guidelines OECD 209 and EPA OPPTS 850.6800 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).

Activated sludge of a predominantly domestic sewage was exposed to the test material for 3 hours at a limit concentration of 1000 mg a.i./L under aerobic conditions. The results show that at a concentration in excess of the water solubility level of the test material, the test material does not have an effect on the respiration rate of activated sewage sludge.

Under the conditions of this study, the 3 h EC50 was greater than 1000 mg ai/L. Correspondingly the No Observed Effect Concentration (NOEC) was 1000 mg ai/L.