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Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

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Reference
Endpoint:
biodegradation in water and sediment: simulation tests
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from predictive model developed by US EPA.
Qualifier:
no guideline available
Principles of method if other than guideline:
Fugacity Model by EPI Suite estimation database
GLP compliance:
no
Radiolabelling:
not specified
Oxygen conditions:
other: estimation
Inoculum or test system:
not specified
Parameter followed for biodegradation estimation:
other: Calculated data
Compartment:
water
% Recovery:
21.2
Remarks on result:
other: Other details not known
Compartment:
sediment
% Recovery:
0.097
Remarks on result:
other: Other details not known
% Degr.:
50
Parameter:
other: Half-life in water
Sampling time:
37.5 d
Remarks on result:
other: 37.5 days = 900 hrs.
% Degr.:
50
Parameter:
other: Half-life in sediment
Sampling time:
337.5 d
Remarks on result:
other: 337.5 days = 8100 hrs.
Compartment:
water
DT50:
37.5 d
Type:
other: estimation
Temp.:
25 °C
Remarks on result:
other: 37.5 days = 900 hrs.
Compartment:
sediment
DT50:
337.5 d
Type:
other: estimation
Temp.:
25 °C
Remarks on result:
other: 337.5 days = 8100 hrs.
Transformation products:
not specified
Evaporation of parent compound:
not specified
Volatile metabolites:
not specified
Residues:
not specified

 

Mass Amount

(percent)

Half-Life

(hr)

Emissions

(kg/hr)

Water

10.8

900

1000

Sediment

3.04

8.1e+003

0

 

 

Fugacity

(atm)

Reaction

(kg/hr)

Advection

(kg/hr)

Reaction

(percent)

Advection

(percent)

Water

6.86e-019

475

617

15.8

20.6

Sediment

8.24e-019

14.8

3.47

0.494

0.116

 

Validity criteria fulfilled:
not specified
Conclusions:
Based on the Estimation Programs Interface Suite (EPI Suite, 2017) prediction model, the half-life in water and sediment for the test compound 2-chloro-p-phenylenediamine (CAS No.615-66-7) is estimated. The half-life period of 2-chloro-p-phenylenediamine in water is calculated as 37.5 days (900 hrs.) while in sediment it is calulated as 337.5 days (8100 hrs).
Executive summary:

Based on the Estimation Programs Interface Suite (EPI Suite, 2017) prediction model, the half-life in water and sediment for the test compound 2-chloro-p- phenylenediamine (CAS No.615-66-7) is estimated. If released into the environment, 21.2% of the chemical will be partitioning into the water according to the Mackay level III fugacity model having an estimated half-life of 37.5 days (900 hrs.). Based on this half-life it is considered that the substance will qualify as not persistent as the half-life does not exceed the threshold of 40 days (to qualify the chemical as persistent in water medium) as per Annex XIII of reach regulation and also it is considered that the exposure risk to aquatic animals is moderate to low. Whereas the half-life period of 2-chloro-p-phenylenediamine in sediment medium is estimated to be 337.5 days (8100 hrs). Therefore it is considered that the substance will qualify as very persistent as the half-life exceeds the threshold of 180 days (to qualify the chemical as very persistent in sediment medium) as per Annex XIII of reach regulation. However, as the percentage release of the test chemical into the sediment is reported as0.0965%, indicates that 2-chloro-p-phenylenediamine is not expected to be persistent in sediment medium.

Description of key information

Based on the Estimation Programs Interface Suite (EPI Suite, 2017) prediction model, the half-life in water and sediment for the test compound 2-chloro-p- phenylenediamine (CAS No.615-66-7) is estimated. The half-life period of 2-chloro-p-phenylenediamine in water is calculated as 37.5 days (900 hrs.) while in sediment it is calulated as 337.5 days (8100 hrs).

Key value for chemical safety assessment

Half-life in freshwater:
37.5 d
at the temperature of:
25 °C
Half-life in freshwater sediment:
337.5 d
at the temperature of:
25 °C

Additional information

Based on the Estimation Programs Interface Suite (EPI Suite, 2017) prediction model, the half-life inwater and sediment for the test compound 2-chloro-p-pheny lenediamine (CAS No.615-66-7) is estimated. If released into the environment, 21.2% of the chemical will be partitioning into the water according tothe Mackay level III fugacity model having an estimated half-life of 37.5 days (900 hrs.). Based on this half-life it is considered that the substance will qualify as not persistent as the half-life does not exceed the threshold of 40 days (to qualify the chemical as persistent in water medium) as per Annex XIII of reach regulation and also it is considered that the exposure risk to aquatic animals is moderate to low. Whereas the half-life period of 2-chloro-p-phenylenediamine in sediment medium is estimated to be 337.5 days (8100 hrs). Therefore it is considered that the substance will qualify as very persistent as the half-life exceeds the threshold of 180 days (to qualify the chemical as very persistent in sediment medium) as per Annex XIII of reach regulation. However, as the percentage release of the test chemical into the sediment is reported as 0.0965%, indicates that 2-chloro-p-phenylenediamine is not expected to be persistent in sediment medium.