Registration Dossier
Registration Dossier
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EC number: 214-901-3 | CAS number: 1208-67-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- for read across
- Justification for type of information:
- Data for the target chemical is summarized based on the structurally similar read across chemicals
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- WoE report is based on toxicity study of microorganism for the test chemical :
1 and 2 ) This study was examined to assess the toxic effects of the test compound on the bacteria in a 24 hours of exposure. - GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: 1. and 2. Bacteria
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 24 h
- Reference substance (positive control):
- not specified
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 500 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The effective concentration (EC0) value of test material in bacteria was found to be 500- 1000 mg/L in a 24 hours of exposure.
- Executive summary:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
For a functionally similar read across substance , this study was examined to assess the toxic effects of the test compound on bacteria in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 1000 mg/L.
Data of another functionally similar read across substance was used to support above data ,this study was examined to assess the toxic effects of the test compound test material on the bacteria in a 24 hours of exposure.The effective concentration (EC0) of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 500 mg/L.
Reference
Description of key information
Toxicity to microorganisms:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
For a functionally similar read across substance , this study was examined to assess the toxic effects of the test compound on bacteria in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 1000 mg/L.
Data of another functionally similar read across substance was used to support above data ,this study was examined to assess the toxic effects of the test compound test material on the bacteria in a 24 hours of exposure.The effective concentration (EC0) of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 500 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 500 mg/L
Additional information
Toxicity to microorganisms:
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of microorganism of the test chemical .The studies are as mentioned below:
For a functionally similar read across substance , this study was examined to assess the toxic effects of the test compound on bacteria in a 24 hours of exposure. The effective concentration (EC0) value of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 1000 mg/L.
Data of another functionally similar read across substance was used to support above data ,this study was examined to assess the toxic effects of the test compound test material on the bacteria in a 24 hours of exposure.The effective concentration (EC0) of test material in bacteria in a 24 hours of exposure on the basis of mortality effect was observed to be 500 mg/L.
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