Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study done to guideline, in compliance with GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
gas under pressure: refrigerated liquefied gas

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
4.7
Temp.:
35 °C
pH:
7
Type:
log Pow
Partition coefficient:
4.8
Temp.:
35 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
In the conditions of the test, the chromatograms of Elintaal show two peaks at average retention times of 14.44 minutes (44.0% relative peak area), corresponding to a partition coefficient (log value) of 4.7 and 15.63 minutes (56.00% relative peak area), corresponding to a partition coefficient (log value) of 4.8.