Registration Dossier
Registration Dossier
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EC number: 215-202-6 | CAS number: 1313-13-9
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
As reported in SIDS Dossier of MnO2 approved at SIAM 25 (17 -18 October 2007) no reliable animal and human data are available for skin sensitization.
This data seems to be confirmed by human study of Motolese et al., 1993: 190 workers (119 females and 71 males) from 5 ceramics factories underwent dermatological and allergological examination, using occupational patch test series. Manganese dioxide caused sensitization only in the two ceramic workers.
Migrated from Short description of key information:
Data-lacking
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
As reported in SIDS Dossier of MnO2 approved at SIAM 25 (17 -18 October 2007) no reliable animal and human data are available for skin sensitization. Due to data-lacking it is not possible to classify or not-classify the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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