Registration Dossier
Registration Dossier
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EC number: 247-640-9 | CAS number: 26381-41-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC was estimated to be 78.421 mg/l when 8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride tested on Daphnia Magna.
Key value for chemical safety assessment
Additional information
Prediction model based estimation of of short term toxicity to aquatic invertebrates was performed. The summary is as mentioned below:
Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10 (2016), the NOEC was estimated to be 78.421 mg/l when 8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride tested on Daphnia Magna.
The median Effective concentration (EC50) value for Basic brown 16 (CAS no 26381 -41 -9) on Daphnia magna in a 48 hour study was estimated to be 721.167053223 mg/L on the basis of mobility.
Though the chemical Basic brown 16 (CAS no 26381 -41 -9) is not readily biodegradable but it has a BCF < 500 and hence the chemical is likely to be "not classified" for aquatic classification as per CLP criteria.
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