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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
ECOSAR v1.1
GLP compliance:
no
Specific details on test material used for the study:
- Name of test material (IUPAC Name): 1,4-Bis(ethenyl)benzene- Common name: p-Divinylbenzene- Molecular formula: C10H10- Molecular weight: 130.189 g/mol- Smiles notation: C(c1ccc(cc1)C=C)=C- InChI: 1S/C10H10/c1-3-9-5-7-10(4-2)8-6-9/h3-8H,1-2H2 - Substance type: Organic- Physical state: Solid- Water solubility: 8.2 mg/l
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
not specified
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
1.744 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: no other details available
Conclusions:
The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Daphnia Magna is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 48 hr exposure, the effect concentration (EC50) for the substance is estimated to be 1.744 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Daphnia Magna at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.
Executive summary:

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Daphnia Magna is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 48 hr exposure, the effect concentration (EC50) for the substance is estimated to be 1.744 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Daphnia Magna at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.

Description of key information

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Daphnia Magna is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 48 hr exposure, the effect concentration (EC50) for the substance is estimated to be 1.744 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Daphnia Magna at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1.744 mg/L

Additional information

The short-term toxicity of the 1,4-Bis(ethenyl)benzene; p-Divinylbenzene (CAS no.105-06-6 ) to Daphnia Magna is predicted using EPI Suite ECOSAR version 1.10. On the basis of effects observed in a static freshwater system during a 48 hr exposure, the effect concentration (EC50) for the substance is estimated to be 1.744 mg/L. Based on this value, it can be concluded that the test chemical can be considered as toxic to Daphnia Magna at environmentally relevant concentrations and can be considered as classified in aquatic chronic category 2 as per the CLP classification criteria.