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EC number: 303-153-4 | CAS number: 94158-80-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data is from review article or handbook
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Acute oral toxicity of 2, 7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
- Author:
- Registry of toxic effect of chemical substances
- Year:
- 2 016
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances)
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: as below
- Principles of method if other than guideline:
- Acute oral toxicity of 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in rats
- GLP compliance:
- not specified
- Test type:
- other: No data
- Limit test:
- no
Test material
- Reference substance name:
- 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
- EC Number:
- 229-413-6
- EC Name:
- 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonic acid
- Cas Number:
- 6522-86-7
- IUPAC Name:
- 5-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonic acid
- Reference substance name:
- 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
- IUPAC Name:
- 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
- Details on test material:
- - Name of test material (as cited in study report): 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo-
- Molecular formula (if other than submission substance): C19H12Cl2N6O7S2
- Molecular weight (if other than submission substance): 571.39 g/mole
- Substance type: Organic
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data available
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- No data available
- Doses:
- 7460 mg/kg bw
- No. of animals per sex per dose:
- No data available
- Control animals:
- not specified
- Details on study design:
- No data available
- Statistics:
- No data available
Results and discussion
- Preliminary study:
- No data available
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 7 460
- Based on:
- test mat.
- Remarks on result:
- other: 50 % mortality observed
- Mortality:
- No data available
- Clinical signs:
- other: No data available
- Gross pathology:
- No data available
- Other findings:
- No data available
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Conclusions:
- LD50 was considered to be 7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.
- Executive summary:
In a acute oral toxicity study,rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- in the concentration of7460 mg/kg bw. 50 % mortality observed in treated rat. Therefore,LD50 was considered to be7460 mg/kg bw when rats were treated with 2,7-Naphthalenedisulfonic acid, 5-(3,5-dichloro-s-triazinylamino) -4-hydroxy-3-phenylazo- orally.
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