Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
evaluation of existing test and data
Type of information:
other: Expert Judgement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
other: expert judgement
Title:
Unnamed
Year:
2017

Materials and methods

Objective of study:
absorption
distribution
excretion
metabolism
toxicokinetics
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Expert judgement with evaluation of toxicokinetic, metabolism and excretion.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate
EC Number:
217-699-5
EC Name:
Trisodium 5-hydroxy-1-(4-sulphophenyl)-4-(4-sulphophenylazo)pyrazole-3-carboxylate
Cas Number:
1934-21-0
Molecular formula:
C16H12N4O9S2.3Na
IUPAC Name:
trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(E)-2-(4-sulfonatophenyl)diazen-1-yl]-4,5-dihydro-1H-pyrazole-3-carboxylate
Test material form:
solid: particulate/powder
Details on test material:
No data
Radiolabelling:
yes

Results and discussion

Metabolite characterisation studies

Metabolites identified:
yes

Applicant's summary and conclusion

Conclusions:
Not bioaccumulative
Executive summary:

Based on the data available, Acid Yellow 23 undergoes to a metabolic degradation into metabolites which are excreted by urine and faeces and therefore Acid Yellow 23 can be considered as not-bioaccumulative.