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Environmental fate & pathways

Hydrolysis

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Reference
Endpoint:
hydrolysis
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Description of key information

Hydrolysis is a common degradation route in the environment, where reaction of a substance with water with a net exchange of the X group with an OH at the reaction centre such that RX + H2O → ROH + HX.

Hydrolysis is often dependent upon pH as the reaction is commonly catalysed by hydrogen or hydroxide ions. Hydrolysis kinetics are usually determined experimentally and should be used to consider the test type and whether parent or degradation product should be tested.

Hydrolyzable organic groups are in fact those groups that can react with water like Esters, Anhydrides, Amides, Carbammates, Nitriles, Cyanates, Epoxides, Halomethanes, Alkylhalides, Urea and none of these groups are present within the substance or their impurities.

Key value for chemical safety assessment

Additional information