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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The LC50of 96 h of test substance FRET 09-0035 on Zebrafish species was 12.89 mg/L (95% confidence limits of 12.03-14.88 mg/L) based on the measured concentrations (geometric average) under the test conditions in this study, according to OECD test guideline 203. Treated group of test substance with nominal concentration of 12.0, 14.0, 16.4, 19.2, 22.5 mg/L (geometric series with a factor of 1.2) and blank control group were designed in the definitive test. 10 fish were used in each group. The duration of test was 96 hours in a semi-static exposure system with renewed test solution every 24 hours. The measured concentrations were within the range of 48.2-95.6% of the nominal concentration at the fresh preparation but changed to 32.8-122.4% after 24 hr exposure. Therefore geometic mean of measured concentration was used for LC50 calculation. According to the statistical analysis, the LC50of 96 h was 12.889 mg/L and 95% confidence limits was 12.032~14.878 mg/L based on the geometric mean of measured concentration.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
12.889 mg/L

Additional information