Benzyltriethylammonium chloride

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Remarks:

pour density; tap density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20/07/2016 – 20/07/2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard OECD test guidelines

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Principles of method if other than guideline:

The density is calculated from the difference in weight between the full and empty pycnometer and its volume

GLP compliance:

no

Type of method:

pycnometer method

Specific details on test material used for the study:

- Name of test material : Benzyltriethylammonium chloride
- IUPAC name: N-benzyl-N,N-diethylethanaminium chloride
- Molecular formula :C13H22NCl
- Molecular weight :227.777 g/mol
- Smiles notation :[N+](CC)(CC)(Cc1ccccc1)CC.[ClH-]
- InChl :1S/C13H22N.ClH/c1-4-14(5-2,6-3)12-13-10-8-7-9-11-13;/h7-11H,4-6,12H2,1-3H3;1H/q+1;/p-1
- Substance type:Organic
- Physical state: White solid crystalline powder
- Purity: 99.80%

Key result

Type:

pour density

Density:

0.646 g/cm³

Temp.:

28.05 °C

Remarks on result:

other: pressure=969.1 hPa

Key result

Type:

tap density

Density:

0.742 g/cm³

Temp.:

28.05 °C

Remarks on result:

other: Pressure=969.1 hPa

TEST ITEM DESCRIPTION AND RESULTS

By Pour Density and Tapped Density Method: 

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1^stReading	2^ndReading
Method	Test methods: Pour density and tapped density of powders”recommended inThe International Pharmacopoeia, Fourth Edition, 2014[1]
Principle of method	Pour Density: It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density:It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)	-	27.7	28.4
Atmospheric pressure (in hPa)	-	970.1	968.1
Weight of test item (m)		20 g	20 g
Volume of measuring cylinder; readability in g		250 ml 2 ml	250 ml 2 ml
Volume of test item without tapping (V)		32 ml	30 ml
Volume of test item after tapping ( V1)	After 10 tapping	28 ml	28 ml
	After 50 tapping	26 ml	28 ml
	After 100 tapping	26 ml	28 ml
	After 250 tapping	-	-
	After 500 tapping	-	-
	After 750 Tapping	-	-

Conclusions:

The mean pour density and tapped density of Triethyl benzyl ammonium chloride (CAS No. 56-37-1) was determine to be 0.6458 g/cm3 and 0.7417 g/cm3 at 28.05°C and 969.1 hPa.

Executive summary:

The mean density of test itemTriethyl benzyl ammonium chloride (CAS No.56-37-1) was determined following OECD Guideline 109 and according to theThe International Pharmacopoeia, Fourth Edition, 2014 using Pour and tap density method.The mean pour density and tapped density of the test item was determine to be 0.6458 g/cm³ and 0.7417 g/cm³ at 28.05^oC and 969.1 hPa.

Description of key information

The mean pour density and tapped density of Triethyl benzyl ammonium chloride (CAS No. 56-37-1) was determine to be 0.6458 g/cm3 and 0.7417 g/cm3 at 28.05°C and 969.1 hPa.

Key value for chemical safety assessment

Relative density at 20C:

0.646

Additional information

The mean density of test itemTriethyl benzyl ammonium chloride(CAS No.56-37-1)was determined following OECD Guideline 109 and according to the International Pharmacopoeia, Fourth Edition, 2014 using Pour and tap density method.The mean pour density and tapped density of the test item was determine to be0.6458 g/cm³ and 0.7417 g/cm³ at 28.05 °C and 969.1 hPa.

Other supporting data from authoritative databases, also exhibited the bulk density of the test substance as 0.7 g/cm3 and density as 1.07 g/cm3.