Registration Dossier
Registration Dossier
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EC number: 202-858-3 | CAS number: 100-50-5
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: limited documented publications
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-Finding Toxicity Data: List VI
- Author:
- Smyth, H.F. et al.
- Year:
- 1 962
- Bibliographic source:
- Am. Ind. Hyg. Ass. J. 23, 95-107
Materials and methods
- Principles of method if other than guideline:
- Method: other in vivo eye irritation study
- GLP compliance:
- no
Test material
- Reference substance name:
- Cyclohex-3-ene-1-carbaldehyde
- EC Number:
- 202-858-3
- EC Name:
- Cyclohex-3-ene-1-carbaldehyde
- Cas Number:
- 100-50-5
- Molecular formula:
- C7H10O
- IUPAC Name:
- cyclohex-3-ene-1-carbaldehyde
- Details on test material:
- 4-Cyclohexene-1-carboxaldehyde
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Test system
- Vehicle:
- not specified
- Controls:
- yes
- Duration of treatment / exposure:
- no data
- Observation period (in vivo):
- no data
- Number of animals or in vitro replicates:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Corneal injury, grading system: 1 to 10
- Basis:
- mean
- Time point:
- other: no data
- Score:
- 8
- Max. score:
- 10
- Reversibility:
- not specified
Any other information on results incl. tables
Corneal injury score 8 of possible 10
Applicant's summary and conclusion
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