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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to terrestrial plants

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Administrative data

Link to relevant study record(s)

Description of key information

The toxicity of o-cresol to lettuce seedlings (Lactuca sativa) was determined according to OECD Guideline 208 in soil. The EC50 was 67 mg/kg soil d.w. after 7 d, >100 mg/kg soil d.w. after 14 d (Hulzebos, 1993). The highest effect concentration (EC50 >100 mg/kg) was normalised to an OC content of 3.4% according to TGD (EU 2003), resulting in a corrected EC50 of >242 mg/kg.

Key value for chemical safety assessment

Short-term EC50 or LC50 for terrestrial plants:
242 mg/kg soil dw

Additional information

The endpoints derived for m-Cresol have been used for this mixed xylenol assessment. Since there are structural and physical chemical similarities between the cresols and the other molecules within the mixed xylenol grouping it is acceptable to assume that their ecotoxicological profiles would be similar.