Registration Dossier
Registration Dossier
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EC number: 603-401-4 | CAS number: 1302-88-1
Repeated dose toxicity: dermal
Administrative data
- Endpoint:
- short-term repeated dose toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- In accordance with Annex VIII of REACH, Column 2, assessing the short-term repeated dose toxicity by the dermal route is relevant only if the inhalation of the substance is unlikely, which is not the case for the registered substance as the substance is a solid generating dust when handle. Moreover due to the particle size of the substance, it cannot be absorbed as such following a dermal exposure. It must first be dissolved for the absorption process to occur. However, the high lattice energy of the structure implies that it would require conditions far more extreme than those the substance will experience on the skin. Therefore no dissolution is expected following a dermal exposure, and no absorption will occur.
Data source
Materials and methods
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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