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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1981
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP study.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1981
Report Date:
1981

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No guideline available in the report as the test has been performed prior to the OECD guideline. Howvere it conforms to the OECD 401 guideline.
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
propylene glycol
Remarks:
Concentration in vehicle: 50 %
Doses:
4,8 ; 5,8 ; 6,9 ; 8,3 and 10 mL/kg
No. of animals per sex per dose:
5 animals per sex per dose
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
4.02 mL/kg bw
Based on:
test mat.
95% CL:
3.34 - 4.85

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: other: GHS EU
Conclusions:
The LD50 of the test substance to male/female Wistar rats was found to be 4.02 ml/kg bw.