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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction mass of 2-{[(2-{3-[2-({[2-(methacryloyloxy)ethoxy]carbonyl}amino)propan-2-yl]phenyl}propan-2-yl)carbamoyl]oxy}propyl methacrylate and 1,3-phenylenebis(propane-2,2-diylcarbamoyloxyethane-2,1-diyl) bis(2-methylacrylate) and 1,3-phenylenebis(propane-2,2-diylcarbamoyloxypropane-2,1-diyl) bis(2-methylacrylate)
EC Number:
943-136-4
Molecular formula:
C26H36N2O8, C27H38N2O8, C28H40N2O8
IUPAC Name:
Reaction mass of 2-{[(2-{3-[2-({[2-(methacryloyloxy)ethoxy]carbonyl}amino)propan-2-yl]phenyl}propan-2-yl)carbamoyl]oxy}propyl methacrylate and 1,3-phenylenebis(propane-2,2-diylcarbamoyloxyethane-2,1-diyl) bis(2-methylacrylate) and 1,3-phenylenebis(propane-2,2-diylcarbamoyloxypropane-2,1-diyl) bis(2-methylacrylate)

Results and discussion

Water solubilityopen allclose all
Water solubility:
0.063 g/L
Conc. based on:
other: Component 1
Incubation duration:
72 h
Temp.:
20 °C
pH:
6.3
Water solubility:
0.045 g/L
Conc. based on:
other: Component 2
Incubation duration:
72 h
Temp.:
20 °C
pH:
6.3
Water solubility:
0.03 g/L
Conc. based on:
other: Component 3
Incubation duration:
72 h
Temp.:
20 °C
pH:
6.3

Applicant's summary and conclusion

Conclusions:
Water solubility is between 0.030 g/L and 0.063 g/L for the individual components of the test item (at 20°C and pH 6.3)
Executive summary:

The water solubility of the test material was determined in a non-GLP test according to OECD Guideline 105, the concentrations of the different test solutions were calculated automatically using the equation of the calibration curve. Water solubility of the main consituents 1 - 3 of the test item are between 0.030 g/L and 0.063 g/L (as a formal value the sum of the components 0.139 g//L can be given) The pH value of the sample solution was 6.3 (6.3, 6.3) after 24 (48, 72) hours of incubation. The water solubility was determined at 20 °C.

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