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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2016-05-09 to 2016-05-10
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OECD Test Guideline 113: Screening Test for Thermal Stability and Stability in Air
Version / remarks:
1981
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
no
Type of method:
dynamic method
Key result
Temp.:
20 °C
Vapour pressure:
0.08 hPa
Temp.:
25 °C
Vapour pressure:
0.11 hPa
Temp.:
50 °C
Vapour pressure:
0.48 hPa

Thermal stability test indicates the test item showed no thermal effects in the temperature range of 25 – 300 °C.

The vapour pressure was measured in the temperature range of 124.0 to 187.1 °C.

The measured vapour pressure values together with the measured temperatures are listed in below table:

No.

Temperature ()

Vapour pressure (hPa)

Remark

1

124.0

13.1

Measured up

2

143.9

24.8

Measured up

3

166.1

49.7

Measured up

4

179.3

74.3

Measured up

5

183.2

83.9

Measured up

6

187.1

94.7

Measured up

7

180.3

77.0

Measured down

8

171.9

59.0

Measured down

9

148.0

29.7

Measured down

From the measured data points of the vapour pressure curve the constants A, B and C of the Antoine equation can be derived by regression (Microsoft Excel) of the data points to A = 9.3549, B = -2480.68, C = 273.15.

The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50°C.

Conclusions:
The vapour pressure of the test item was found to be 0.08 hPa at 20 °C, 0.11 hPa at 25 °C and 0.48 hPa at 50°C.
Executive summary:

In the current study the vapour pressure of the test item was assessed according to the OECD guideline 104 (dynamic method: vapour-liquid equilibrium). It was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50°C. The vapour pressures are 0.08, 0.11 and 0.48 hPa for 20, 25 and 50°C respectively.

Description of key information

The vapour pressure of the test item is determined by means of the dynamic vapour-liquid equilibrium method and was found to be 0.08 hPa at 20 °C, 0.11 hPa at 25 °C, 0.48 hPa at 50 °C, respectively.

Key value for chemical safety assessment

Vapour pressure:
0.08 hPa
at the temperature of:
20 °C

Additional information

For this endpoint one study is available in which according to the OECD guideline 104 (dynamic method: vapour-liquid equilibrium) the vapour pressure of the test item was calculated by extrapolation for the temperatures 20, 25 and 50°C of the measured vapour pressure curve.

The vapour pressures are 0.08, 0.11 and 0.48 hPa for 20, 25 and 50°C respectively.