Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Link to relevant study records
Reference
Endpoint:
carcinogenicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Guideline:
other: see attached SCCP study report
GLP compliance:
no
Species:
mouse
Strain:
Swiss
Sex:
female
Route of administration:
dermal
Vehicle:
acetone
Duration of treatment / exposure:
108 weeks
Frequency of treatment:
2 applications weekly
Remarks:
Doses / Concentrations:
1, 5 and 10% in acetone
Basis:

No. of animals per sex per dose:
50
Dose descriptor:
T25
Effect level:
> 10 other: percent
Based on:
test mat.
Sex:
female
Remarks on result:
not determinable
Remarks:
no T25 identified. Effect type:carcinogenicity (migrated information)
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
T25
Study duration:
chronic
Species:
mouse

Justification for classification or non-classification

Based on the available study the substance is not to be classified under REACH and CLP as carcinogenic

Additional information