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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
European Commission
Year:
2006
Bibliographic source:
SCCP/1008/06

Materials and methods

Test guideline
Guideline:
other: no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-aminobenzoic acid
EC Number:
205-753-0
EC Name:
4-aminobenzoic acid
Cas Number:
150-13-0
Molecular formula:
C7H7NO2
IUPAC Name:
4-aminobenzoic acid

Test animals

Species:
rat
Strain:
Wistar
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Duration of treatment / exposure:
108 d

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Effect level:
>= 1 200 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
female
Remarks on result:
not determinable
Remarks:
no NOAEL identified

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion