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Toxicity to aquatic algae and cyanobacteria

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toxicity to aquatic algae and cyanobacteria
Type of information:
Adequacy of study:
supporting study
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
Test organisms (species):
other: Green algae
Test type:
other: (Q)SAR
Water media type:
96 h
Dose descriptor:
Effect conc.:
83.615 mg/L
Basis for effect:
growth rate
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
16.122 mg/L
Validity criteria fulfilled:
Esters: Maximum LogKow: 6.4 (Green Algae EC50) - 8.0 (Chronic Value)
Estimated EC50 : 83 mg/L
Estimated Chronic Value : 16 mg/L
Intermediate substance is not estimated to be toxic to aquatic algae

Description of key information

ECOSAR 1.11: Green Algae: EC50 (96h): 83 mg/L


Danish (Q)SAR Database: Pseudokirchneriella s. 72h EC50:

Battery: 90 mg/L

Leadscope: 155 mg/L

SciQSAR: 25 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
83 mg/L
EC10 or NOEC for freshwater algae:
16 mg/L

Additional information

Lowest NOEC could be estimated to around 11 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is not estimated to be toxic to aquatic algae.


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