Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute valid data, based on international guidelines, are available for three trophic levels: Algae Aquatic Invertebrates and Fish; and on Microorganisms. These data are summarised in the table below:

Level of exposure / trophic levels

Test substance

Organism

EC50/LC50

EC10/NOEC

Flag / reliability

Performing laboratory

Reference in IUCLID

Acute / Aquatic algae

Registered substance

Desmodesmus subspicatus

72h: 20 mg/L (growth rate)

72h: 11 mg/L (growth rate)

K/2

Harlan

Toxicity to aquatic algae and cyanobacteria, 2008, Goodband, RS, K

Acute / Aquatic invertebrates

Registered substance

Daphnia magna

48h: 15 mg/L

-

K/2

Safepharm

Short-term toxicity to aquatic invertebrates, 2008, Goodband, RS, K

Acute / Fish

Registered substance

Brachydanio rerio

96h: 13.1 mg/L

-

K/2

Supervision and Test Center for Pesticide Safety Evaluation and Quality Control

Short-term toxicity to fish, Zhao, 2008, RS, K

Acute / Micro-organisms

Registered substance

activated sludge

3h: 700 mg/L

3h: 180 mg/L

K/2

Safepharm

Toxicity to microorganisms, 2008, Clarke, RS, K

Among data available, the fish, Brachydanio rerio, is the most sensitive species with a 96h-LC50 at 13.1 mg/L. For aquatic invertebrates, the 48h-EC50 was determined at 15 mg/L. For algae, the 72h-EC50 value was determined at 20 mg/L (based on growth rate). For microorganisms, the 3h-EC50 and 3h-NOEC values were determined at 700 mg/L and 180 mg/L respectively.