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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The NOEC (highest concentration tested without toxic effect) of FAT20004/H was determined to be 10.0 mg test article/1. The 48 hour EC 50 could not be specified. Hence LC50 is concluded to be greater than 100mg/L.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
100 mg/L

Additional information

The acute toxicity of FAT 20004/H to Daphnia magna was determined in a 48-hour static test according to the OECD Guideline for Testing of Chemicals, Section 2, No. 202, adopted 4 April 84, the EEC Directive 84/449, L 251, Part C 2, and to the Guideline of the U.S. Environmental Protection Agency, Pesticide. Assessment Guidelines, Subdivision E, EPA-540/9-85-005, June, 1985 and in compliance with GLP.

The nominal concentrations tested were 0.65, 1.25, 2.5, 5.0 and 10.0 mg/L of test substance, a solvent control group and a control without any additions.

In the control, the solvent control group and in the test concentrations of nominal 0.65 to 5.0 mg test article, no immobility or mortality was observed during test duration. In the highest concentration tested of 10.0 mg test article (as the highest concentration as possible to dissolve in dimethylformamid at room temperature and an addition of 100 ul solvent stock solution to 1 litre test medium) the immobility rate was 5 % after 24 and 48 hours test duration. Because of this low immobilization rate, the NOEC (highest concentration tested without toxic effect) of FAT 20004/H was determined to be 10.0 mg test article. The 48 hour EC 50 could not be specified.