Registration Dossier

Administrative data

Endpoint:
epidemiological data
Type of information:
other: epidemiology study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: MIGRATED DATASET. Original reference not available.

Data source

Reference
Title:
No information
Author:
DuPont (1985). Mortality and cancer incidence among workers exposed to 1,4-dichlorobutene-2 at the Victoria plant. Haskell Laboratory, Epidemiology Section, medical Division, Employee Relations Department. Report from January 1985 (NTIS OTS 509754).

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Type of population:
occupational
Ethical approval:
not specified
Details on study design:
An epidemiology study was conducted on 598 male workers exposed to 1,4-dichlorobut-2 ene at the Victoria plant of DuPont Co. in Texas, USA from 1956 through 1983 for cancer incidence, and from 1957 through 1980 for mortality.

Results and discussion

Results:
By comparing the mortality and cancer rates of the DuPont Company with the US national rates, the results did not indicate that employees are at an increased risk of developing cancer.
Strengths and weaknesses:
The validity of this study suffers from its limited statistical power due to the small size of the cohort.

Applicant's summary and conclusion