Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19 May - 04 Jun 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with national standard methods under GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): MTDID 15655
- Physical state: yellowish viscous liquid
- Analytical purity: 91.4%
- Expiration date of the lot/batch: 27 August 2017
- Storage condition of test material: at room temperature

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0 Pa
Remarks on result:
other: 1.0E-10 mm Hg
Temp.:
25 °C
Vapour pressure:
0 Pa
Remarks on result:
other: 2.6E-10 mm Hg

Applicant's summary and conclusion

Conclusions:
The vapor pressure of Z-Acetate is 1.3E-08 Pa (1.0E-10 mm Hg) at 20 °C and 3.5E-08 Pa (2.6E-10 mm Hg) at 25 °C as determined by the OECD 104 method.
Executive summary:

The vapor pressure of the test substance was determined by the isothermal thermogravimetric effusion method. The weight loss of the sample was measured at 4 isothermal points between 180 and 210°C. Weight loss rate at each temperature was converted to vapor pressure and entered into linear regression analysis vs. temperature. The resulting equation was log P(T) = -7242 ×1/T + 16.83 (r = 0.995). The test was done according to EU Method A.4 “Vapour pressure” and OECD 104 “Vapour Pressure Curve” and in accord with GLP guidelines; therefore this study is classified as reliable without restrictions.