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EC number: 245-844-2
CAS number: 23726-93-4
OECD Guideline 301F, EU Method C.4-D, GLP, key study, validity 2:65% biodegradation after 28 days but failing the 10-day window.77% biodegradation after 48 days.Not readily biodegradable but not persistent.
To assess the biodegradation potential of
the registered substance, one experimental key study is available.
study (Givaudan, 2013) was performed on the registered substance
according to OECD Guideline No. 301F and EU Method C.4-D with GLP
test substance was exposed to activated sewage sludge micro-organisms at
a concentration of 30 mg/L with culture medium in sealed culture vessels
in the dark at 21°C for 28 days. The degradation of the test substance
was assessed by the measurement of daily oxygen consumption. Control
solutions with inoculum and the standard material (sodium benzoate) were
used for validation purposes. However, no toxicity control was
65% biodegradation after 28 days and 77% biodegradation after 48 days in
the test conditions. The 10-day window criterion is not fulfilled (14%
biodegradation on day 11 and 52% on day 21). Degradation of sodium
benzoate exceeds 40 % after 7 days and 65 % after 14 days: the activity
of the inoculum is thus verified. In conclusion, under the test conditions,
test substance should be regarded as not readily biodegradable. However,
based on the results the test substance should be regarded as not
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