Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Gene mutation in bacteria (OECD 471): Negative

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

The genotoxicity of the test substance Cassia oil was tested according to OECD TG 471 (Ames test) and under GLP conditions. No significant increases in the frequency of revertant colonies were recorded for any of the bacterial strains, with any dose of the test item, either with or without metabolic activation or exposure method. Based on the results of this Ames test, the test item Cassia oil was considered to be non-mutagenic under the conditions as specified.

Justification for classification or non-classification

Based on the results of the Ames test, the substance is not mutagenic and therefore it does not have to be classified for mutagenicity in accordance with the criteria outlined in Annex I of 1272/2008/EC (CLP/EU-GHS).