Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-276-6 | CAS number: 611-71-2
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06-05-2002 to 21-05-2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study (OECD), validity criteria fulfilled
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- L-2-hydroxy-2-phenylacetic acid
- EC Number:
- 210-276-6
- EC Name:
- L-2-hydroxy-2-phenylacetic acid
- Cas Number:
- 611-71-2
- Molecular formula:
- C8H8O3
- IUPAC Name:
- hydroxy(phenyl)acetic acid
- Details on test material:
- ChiPros (R)-Mandelsäure: (R)-mandelic acid (purity: 100 %)
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 14 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Initial conc.:
- 32 mg/L
- Based on:
- test mat.
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Value:
- ca. 90 - ca. 100
- Sampling time:
- 14 d
- Details on results:
- RS-Freetext:
DOC (mg/l, average values):
time BC RS IH PC AC TS
(d)
0 0.3 20.0 41.3 21.5 21.6 21.4
1 0.3 20.6 41.5 21.4 22.0 21.4
3 1.9 18.2 20.3 21.7 22.2 2.4
5 0.5 2.1 2.9 21.3 21.9 1.2
7 1.6 2.6 3.0 21.9 1.5
10 0.8 2.5 2.9 21.6 1.1
13 1.1 2.6 2.4 22.0 1.1
14 0.8 2.2 2.0 22.0 1.2
DOC decrease (%):
time RS IH PC AC TS
(d)
0 0 0 0 0 0
1 -3 0 0 -1 -2
3 17 55 -1 5 100
5 92 94 1 0 97
7 95 97 -2 100
10 91 95 0 99
13 92 97 -2 100
14 93 97 -2 99
BC = blank control
RS = reference substance
IH = inhibition control
PC = abiotic control
AC = adsorption control
TS = test substance
- adaptation phase: 1-2 days
- degradation phase: 1-2 days
- 10-day window met: yes
Kinetic of test substance (in %):
< 0 after 1 day(s)
ca. 100 after 3 day(s)
ca. 100 after 7 day(s)
ca. 99 after 14 day(s)
Kinetic of control substance (in %):
ca. 90 ... 100 after 14 day(s)
Degradation products: not measured
Any other information on results incl. tables
preliminary investigations (non-GLP):
- TOC = 627 mg/g
- DOC = 634 mg/g
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
