Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to international accepted guidelines, but not GLP compliant.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Details on test material:
Test item: 4-nitrophenyl-acetic acid
CAS number: 104-03-0
EC number: 203-168-5
Molecular formula: C8H7NO4
Molecular weight: 181.15 g/mol
Physical state: Solid, crystalline powder
Colour: Yellowish to yellow-brownish
Storage: Cool, dry place, protected from light

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
30 °C
pH:
7.72

Applicant's summary and conclusion