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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

fish early-life stage toxicity
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study scientifically not necessary / other information available
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Description of key information

The HYDROTOPES Category comprises the following 6 substances:
STS - Sodium toluene sulphonate (CAS 657-84-1, EC 211-522-5)
SXS - Sodium (xylenes and 4-ethylbenzene) sulphonate (EC 701-037-1)
NH4XS - Ammonium (xylenes and 4-ethylbenzene) sulphonate (EC 943-024-5)
SCS - Sodium cumene sulphonate (CAS 15763-76-5, EC 239-854-6)
KCS - Potassium cumene sulphonate (CAS 164524-02-1, EC 629-764-9)
NH4CS - Ammonium cumene sulphonate (CAS 37475-88-0, 253-519-1) 
In addition CaXS (Calcium Xylenesulphonate, CAS 28088-63-3, EC248-829-9)was evaluated for complete the assessment despite it is not registered under REACH.

An environmental risk assessment has indicated that the members of the Hydrotropes category do not pose a risk to the aquatic environment for all relevant uses. In Annex IX of Regulation (EC) No 1907/2006 it is laid down that chronic toxicity tests shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further. There are available acute tests on the three hydrotropes subgroups (toluene, xylene and cumene) which did not show any concern for all the three thropic levels. Since the chronic testing would not change the outcome of the environmental risk assessment the additional chronic testing on aquatic invertebrates appears to be unjustified. One chronic test on invertebrates is available (Huels, 1987), but is considered of poor reliability (Klimisch 4). The study indicates a long term chronic toxicity of sodium cumene sulfonate to Daphnia magna of a NOEC of <30 or 30 mg/L and an LC50 of 154 mg/L. Use of these data, would not change the outcome of the environmental risk assessment and are provided for completeness only. As acute toxicity was not observed at the concentrations tested in the acute studies and the hydrotrope category members are readily biodegradable, no additional chronic testing on aquatic invertebrates is required and this endpoint is waived.

Key value for chemical safety assessment

Additional information