Registration Dossier
Registration Dossier
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EC number: 223-395-3 | CAS number: 3874-54-2
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study according to internetional accepted guidelines but not GLP compliant.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- HPLC method
- Remarks:
- reverse phase
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 4-chloro-4'-fluorobutyrophenone
- EC Number:
- 223-395-3
- EC Name:
- 4-chloro-4'-fluorobutyrophenone
- Cas Number:
- 3874-54-2
- Molecular formula:
- C10H10ClFO
- IUPAC Name:
- 4-chloro-1-(4-fluorophenyl)butan-1-one
- Test material form:
- other: liquid
- Details on test material:
- Test item: 4-chloro-4’-fluorobutyrophenoneCAS No.: 3874-54-2Batch No.: 2607Physical state: liquidColour: yellowish green/ yellowStorage: cool, dry place in a tightly closed container
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.84
- Temp.:
- 30 °C
- Remarks on result:
- other: HPLC method
- Details on results:
- The value of partition coefficient of 4-chloro-4’-fluorobutyrophenone was determined by Microsoft Office Excel 2007.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
