Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
-
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
-
Deviations:
no
GLP compliance:
no
Type of method:
capillary method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4-Diamino-6-chloropyrimidine-3-oxide
EC Number:
609-076-5
Cas Number:
35139-67-4
Molecular formula:
C4H5ClN4O
IUPAC Name:
2,4-Diamino-6-chloropyrimidine-3-oxide
Test material form:
solid
Remarks:
white/beige solid
Specific details on test material used for the study:
- Analytical purity: > 99%- Lot/batch No.: 0160405- Expiration date of the lot/batch: 21/02/2018

Results and discussion

Melting / freezing point
Key result
Atm. press.:
ca. 1 atm
Decomposition:
yes
Decomp. temp.:
ca. 179.9 °C

Any other information on results incl. tables

Pre-Test

Begin of changes was visible at 192.7 °C (getting darker). The test substance was completely black at 195.3 °C. The last changes were nearly explosively.Decomposition was stated.

Main Study

The following values were recorded:

Values Main Study

Decomposition

Begin

End

First determination

180.0 °C (453.2 K)

182.2 °C (455.4 K)

Second determination

179.9 °C (453.1 K)

181.7 °C (454.9 K)

Validity

As the test substance decomposes no validity criteria must be considered.

Result

The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test substance.

 

Beginning decomposition was determined with

 179.9 °C (453.1 K)

 Signs for explosive properties were visible.

Applicant's summary and conclusion

Conclusions:
The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test substance. Beginning decomposition was determined with 179.9 °C (453.1 K). Signs for explosive properties were visible.
Executive summary:

The melting point of the test item was investigated with a not-GLP compliant study, following the standard guideline OECD TG 102 (capillary method). The determination was performed in duplicate. In both determinations, no melting point could be detected, because of decomposition of the test item. Beginning decomposition was determined with 179.9 °C (453.1 K). Signs for explosive properties were visible.